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Dr. Goutam Ghosh

"Do not go where the path may lead, go instead where there is no path and leave a trail."

 -- Ralph Waldo Emerson

   

  Visitor number

UGC-DAE Consortium for Scientific Research, Mumbai Centre

R-5 Shed, BARC Campus, Trombay, Mumbai 400085,India

Phone: +91 22 25594727, 25505327

Fax:     +91 22 25505402

email: ghoshg@csr.res.in, ghoshg@yahoo.com

Bio/Nano interface research

Phenomena at the bio/nano interface seems to be very interesting and promising for biomedical applications. A counterions bound coating on nanoparticles may show an excellent use of nanoparticles in therapy. Our recent reports show that on electrostatic binding of proteins with these nanoparticles associated counterions unfold the native conformations of bound proteins. A model, called Reverse Charge Parity Counterions (RCPC), has been developed to define the protein-nanoparticle e.s. interaction and counterions effect. The interactions have been theoretically formulated in CSB 2015, a representative artwork of this model has been published in the Cover Page of this issue (see Research page). A layman summary of this paper can be seen in Atlas of Science. The counterions bound charge-ligand coated iron oxide nanoparticles also show interesting magnetic properties.

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